SCHEMBL144688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1919069	0.93	CYP2C8 (0.53)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL10242345	0.93	CYP2C8 (0.53)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL18751750	0.92	CYP2C8 (0.52)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL18751755	0.91	CYP2C8 (0.55)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL1919345	0.90	CYP2C8 (0.58)	CYP2C8KCNH2CYP3A4ANO1NR1I2
	SCHEMBL1919284	0.90	CYP2C8 (0.50)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL1918814	0.90	CYP2C8 (0.50)	CYP2C8KCNH2CYP3A4MAPTTP53
	SCHEMBL254263	0.89	CYP2C8 (0.49)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL12447846	0.86	CYP2C8 (0.52)	CYP2C8KCNH2CYP3A4ANO1MAPT
	SCHEMBL143697	0.86	CYP2C8 (0.55)	CYP2C8KCNH2CYP3A4ANO1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.