Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 16/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468966 | 0.93 | F2R (0.69) | F2RMAPT | |
| SCHEMBL14468892 | 0.93 | F2R (0.82) | F2RMAPTGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL12167167 | 0.93 | F2R (0.82) | F2R | |
| SCHEMBL14468937 | 0.93 | F2R (0.68) | F2RMAPTGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL14469081 | 0.92 | F2R (0.67) | F2RMAPTGAASMN1; SMN2 | |
| SCHEMBL14468887 | 0.91 | F2R (0.59) | F2RGAA | |
| SCHEMBL12151669 | 0.91 | F2R (0.66) | F2RMAPTSMN1; SMN2 | |
| SCHEMBL14468894 | 0.91 | F2R (0.66) | F2RMAPTSMN1; SMN2 | |
| SCHEMBL14468855 | 0.91 | F2R (0.82) | F2RGAA | |
| SCHEMBL12151796 | 0.90 | F2R (0.63) | F2RGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |