Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 14/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373859 | 0.83 | CXCR3 (0.71) | CXCR3MEN1KMT2A | |
| SCHEMBL14373396 | 0.82 | CXCR3 (0.82) | CXCR3 | |
| SCHEMBL14373646 | 0.81 | CXCR3 (0.56) | CXCR3MAPT | |
| SCHEMBL14373405 | 0.81 | CXCR3 (0.82) | CXCR3 | |
| SCHEMBL14373625 | 0.80 | CXCR3 (0.57) | CXCR3MEN1KMT2A | |
| SCHEMBL14373638 | 0.79 | CXCR3 (0.50) | CXCR3KMT2AMAPT | |
| SCHEMBL14373631 | 0.79 | CXCR3 (0.55) | CXCR3MEN1KMT2A | |
| SCHEMBL14373619 | 0.78 | CLK2 (0.60) | CXCR3MEN1KMT2A | |
| SCHEMBL14373642 | 0.78 | CXCR3 (0.54) | CXCR3MEN1KMT2A | |
| SCHEMBL14373324 | 0.77 | CXCR3 (0.74) | CXCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |