Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373496 | 0.82 | CXCR3 (0.76) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14373658 | 0.81 | CXCR3 (0.68) | CXCR3KMT2AMEN1ATMKDM4E | |
| SCHEMBL14400625 | 0.80 | CXCR3 (0.67) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14373656 | 0.80 | CXCR3 (0.67) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14373657 | 0.79 | CXCR3 (0.64) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14470443 | 0.78 | CXCR3 (0.63) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14373661 | 0.77 | CXCR3 (0.61) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14470558 | 0.73 | CXCR3 (0.56) | CXCR3KMT2AMEN1ATMKDM4E | |
| SCHEMBL5465834 | 0.71 | CXCR3 (0.72) | CXCR3KMT2AMEN1ATMMAPT | |
| SCHEMBL14373266 | 0.71 | CXCR3 (0.94) | CXCR3KMT2AMEN1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |