Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269285 | 0.88 | PDE4B (0.39) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL31108115 | 0.85 | PDE4B (0.39) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269286 | 0.83 | PDE4B (0.37) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269287 | 0.82 | PDE4B (0.41) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269001 | 0.82 | PDE4B (0.41) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10269283 | 0.82 | PDE4B (0.40) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL30279976 | 0.78 | NAAA (0.38) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL21239438 | 0.78 | NAAA (0.38) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL28862941 | 0.78 | NAAA (0.38) | CHRM1PDE4AADRA1APDE1APDE4B | |
| SCHEMBL10268045 | 0.78 | MEN1 (0.38) | CHRM1PDE4AADRA1APDE1APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | disclosed |