SCHEMBL144720

SCHEMBL144720

CC[C@H]1CC[C@H]2[C@@H]3CCC4CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 2/20 0.55
GRIN2B Q13224 2/20 0.55
CYP19A1 P11511 1/20 0.52
GPBAR1 Q8TDU6 3/20 0.51
LMNA P02545 3/20 0.51
EPHA2 P29317 2/20 0.51
HSD17B10 Q99714 2/20 0.51
AKR1B10 O60218 1/20 0.51
AKR1B1 P15121 1/20 0.51
EFNA1 P20827 1/20 0.51
PSEN1 P49768 1/20 0.51
PSEN2 P49810 1/20 0.51
APH1B Q8WW43 1/20 0.51
NCSTN Q92542 1/20 0.51
APH1A Q96BI3 1/20 0.51
PSENEN Q9NZ42 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
SHBG P04278 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350132 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
SCHEMBL20677083 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
SCHEMBL29875956 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
SCHEMBL28175592 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
SCHEMBL19313988 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
SCHEMBL144721 1.00 GRIN1 (0.55) GRIN1GRIN2BCYP19A1GPBAR1LMNA
Bromide SCHEMBL16178922 0.98 GRIN1 (0.54) GRIN1GRIN2BCYP19A1GPBAR1LMNA
Bromide SCHEMBL16178917 0.98 GRIN1 (0.54) GRIN1GRIN2BCYP19A1GPBAR1LMNA
Charcoal, Activated SCHEMBL30693761 0.98 GRIN1 (0.54) GRIN1GRIN2BCYP19A1GPBAR1LMNA
Water SCHEMBL28180475 0.98 GRIN1 (0.54) GRIN1GRIN2BCYP19A1GPBAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5793 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144802-A1 POST-OPERATIVE DELIRIUM SUPPRESSANT NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2026-05-28 US claimed
EP-3818068-B1 NEUROACTIVE STEROIDS AND METHODS OF PREPARATION DRAWBRIDGE PHARMACEUTICALS PTY LTD (AU) 2025-10-29 EP claimed
US-12350381-B2 Nanoparticles containing cellular membrane and uses thereof ARYTHA BIOSCIENCES, LLC (US) 2025-07-08 US claimed
WO-2025125889-A1 PREGNANE X RECEPTOR (PXR) ANTAGONISTS FOR THE TREATMENT OF DENGUE FEVER CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL I.P.N. (MX) 2025-06-19 WO claimed
EP-4569334-A1 6-POSITION-MODIFIED STEROIDS AND USES THEREOF Beckman Coulter, Inc. (US) 2025-06-18 EP claimed
CN-120129683-A Azole derivatives as SHP2 inhibitors IRBM股份公司 2025-06-10 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120022371-A Organic molecule self-assembly body used as material-free drug carrying system, and preparation method and application thereof 四川大学华西医院 2025-05-23 CN claimed
CN-119751535-A Preparation method of pregnane ketone 浙江仙琚制药股份有限公司 2025-04-04 CN claimed
CN-119678050-A 6-Modified steroids and uses thereof 贝克曼库尔特有限公司 2025-03-21 CN claimed
US-4036831-A Trimethyl siloxane steroid intermediates STEROID DEVELOPMENT COMPANY ESTABLISHMENT (CH) 1977-07-19 US claimed
US-4011316-A STEROIDS, ANTIINFLAMMATORY AGENTS RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) 1977-03-08 US claimed
US-3984544-A Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor SCHERING CORPORATION (US) 1976-10-05 US claimed
US-3980680-A Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein SCHERING CORPORATION (US) 1976-09-14 US claimed
US-3962217-A Process for the manufacture of Δ16 -steroid-14β,18,20-triols and -14β,20-diol-18-ols of the pregnane series CIBA-GEIGY CORPORATION (US) 1976-06-08 US claimed
US-3959320-A Process and compounds THE UPJOHN COMPANY (US) 1976-05-25 US claimed
US-3933799-A HORMONES GLAXO LABORATORIES LIMITED (EN) 1976-01-20 US claimed
US-3933869-A Preparation of organic radiohalogen compounds SCHERING AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed
US-3930970-A PHOTOLYSIS OF ALCOHOL NITRITES RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) 1976-01-06 US claimed
US-3931167-A Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein SCHERING CORPORATION (US) 1976-01-06 US claimed