Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677083 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| SCHEMBL29875956 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| SCHEMBL28175592 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| SCHEMBL19313988 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| SCHEMBL144721 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| SCHEMBL144720 | 1.00 | GRIN1 (0.55) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| Bromide SCHEMBL16178922 | 0.98 | GRIN1 (0.54) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| Bromide SCHEMBL16178917 | 0.98 | GRIN1 (0.54) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| Charcoal, Activated SCHEMBL30693761 | 0.98 | GRIN1 (0.54) | GRIN1GRIN2BCYP19A1GPBAR1LMNA | |
| Water SCHEMBL28180475 | 0.98 | GRIN1 (0.54) | GRIN1GRIN2BCYP19A1GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321686-B1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON INC (US) | 2024-03-13 | — | — | EP | claimed |
| EP-3965773-A1 | NOVEL METHOD FOR SYNTHESIZING 25-OH CHOLESTEROL/CALCIFEDIOL FROM PHYTOSTEROL | Fermenta Biotech Limited (IN) | 2022-03-16 | — | — | EP | claimed |
| EP-3321686-A1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2018-05-16 | — | — | EP | claimed |
| EP-2951313-B1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON INC (US) | 2018-03-07 | — | — | EP | claimed |
| US-9910047-B2 | Biomarkers related to insulin resistance progression and methods using the same | METABOLON, INC. (US) | 2018-03-06 | — | — | US | claimed |
| CN-106231908-A | System for pest extermination, inhibition or control | 埃梅卡泰克有限责任公司 | 2016-12-14 | — | — | CN | claimed |
| US-20150362510-A1 | Biomarkers Related to Insulin Resistance Progression and Methods Using the Same | METABOLON, INC. | 2015-12-17 | — | — | US | claimed |
| EP-2667876-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | Harbor BioSciences, Inc. (US) | 2013-12-04 | — | — | EP | claimed |
| EP-1812009-B1 | GABA-STEROID ANTAGONISTS AND THEIR USE FOR THE TREATMENT OF CNS DISORDERS | UMECRINE AB (SE) | 2013-05-15 | — | — | EP | claimed |
| WO-2012083090-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | HARBOR BIOSCIENCES, INC. (US) | 2012-06-21 | — | — | WO | claimed |
| EP-1082319-B1 | BENZOCARBAZOLE AND INDENOINDOLE DERIVED ESTROGENIC AGENTS | WYETH CORP (US) | 2006-09-13 | — | — | EP | claimed |
| WO-2004093891-A1 | VEGETABLE EXTRACT COMPOSITIONS COMPRISING INODOLE ACETIC, METHODS FOR THE PREPARATION OF SAID COMPSITIONS, AND THEIR USE AS CELL GROWTH INHIBITING AGENTS | VEIJLEN N.V. (AN) | 2004-11-04 | — | — | WO | claimed |
| EP-1082319-A1 | BENZOCARBAZOL AND INDENOINOLE DERIVED ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-03-14 | — | — | EP | claimed |
| US-6159959-A | Combined estrogen and antiestrogen therapy | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-12 | — | — | US | claimed |
| WO-1999058524-A1 | BENZOCARBAZOLE AND INDENOINDOLE DERIVED ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | claimed |
| US-20250313905-A1 | METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-10-09 | — | — | US | disclosed |
| US-20250213591-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| EP-0527962-A4 | METHOD, COMPOSITIONS, AND COMPOUNDS FOR MODULATING BRAIN EXCITABILITY | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0527962-A1 | METHOD, COMPOSITIONS, AND COMPOUNDS FOR MODULATING BRAIN EXCITABILITY | GEE, Kelvin W. (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991016897-A1 | METHOD, COMPOSITIONS, AND COMPOUNDS FOR MODULATING BRAIN EXCITABILITY | WELLMAN GEE KELVIN (US) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213591-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | GAP43, HSD3B1, CYP17A1 | GRIN1 133/4885GRIN2B 134/4885CYP19A1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.