Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.86 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.86 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.86 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84865 | 0.93 | PDE4A (1.00) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7398485 | 0.91 | PDE4A (0.96) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL14455896 | 0.84 | PDE4A (0.84) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7395757 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7400689 | 0.74 | PDE4A (0.81) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7369182 | 0.73 | PDE4A (0.67) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7401440 | 0.72 | PDE4A (0.79) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7369940 | 0.71 | PDE4A (0.80) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7374697 | 0.70 | PDE4A (1.00) | PDE4APDE4BPDE4DPDE4CADORA3 | |
| SCHEMBL7376577 | 0.70 | PDE4A (1.00) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810692-A1 | REMEDIES/PREVENTIVES FOR CHRONIC SKIN DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-25 | — | — | EP | disclosed |