Hexamidine

Hexamidine

SCHEMBL144738

N=C(N)c1ccc(OCCCCCCOc2ccc(C(=N)N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 1.00
F2 P00734 2/20 1.00
ST14 Q9Y5Y6 2/20 1.00
TMPRSS2 O15393 2/20 1.00
PLAU P00749 1/20 1.00
PRMT5 O14744 1/20 1.00
SLC22A2 O15244 1/20 1.00
SLC22A1 O15245 1/20 1.00
PTP4A3 O75365 1/20 1.00
SLC22A3 O75751 1/20 1.00
F10 P00742 1/20 1.00
PLG P00747 1/20 1.00
S100B P04271 1/20 1.00
CHRM2 P08172 1/20 1.00
CHRM4 P08173 1/20 1.00
CHRM5 P08912 1/20 1.00
ADRA2A P08913 1/20 1.00
CYP2D6 P10635 1/20 1.00
AOC1 P19801 1/20 1.00
MAOA P21397 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14599628 1.00 PRMT1 (1.00) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL14599631 1.00 PRMT1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Heptamidine SCHEMBL14599630 1.00 PRMT1 (1.00) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL14599639 1.00 PRMT1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Pentamidine SCHEMBL3329 1.00 PRMT1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Pentamidine SCHEMBL3227 0.98 PRSS1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Hexamidine SCHEMBL306398 0.98 PRMT1 (0.96) PRMT1F2ST14TMPRSS2PLAU
Pentamidine SCHEMBL7060561 0.98 PRSS1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Hexamidine SCHEMBL3629982 0.98 PRSS1 (1.00) PRMT1F2ST14TMPRSS2PLAU
Hexamidine SCHEMBL18701066 0.98 PRMT1 (0.96) PRMT1F2ST14TMPRSS2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6901 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743053-A1 ANTIMICROBIAL SYNERGIES Symrise AG (DE) 2026-05-20 EP claimed
EP-3313534-B1 SUPERABSORBENT POLYMERS AND STARCH POWDERS FOR USE IN SKIN CARE COMPOSITIONS PROCTER & GAMBLE (US) 2026-05-20 EP claimed
EP-4727514-A1 DEODORANT COMPOSITIONS COMPRISING CARBOXYLIC ACIDS The Procter & Gamble Company (US) 2026-04-22 EP claimed
US-20260083648-A1 DEODORANT COMPOSITIONS AND METHODS OF MAKING SAME DR. SQUATCH, LLC (US) 2026-03-26 US claimed
EP-4554551-B1 3-HYDROXYPROPYLESTERS AS ANTIMICROBIAL AGENTS SYMRISE AG (DE) 2026-03-11 EP claimed
EP-4701417-A1 ANTIMICROBIAL COMPOSITIONS CONTAINING A CATIONIC ANTIMICROBIAL AND AN ACIDIC GLYCOLIPID LANXESS Corporation (US) 2026-03-04 EP claimed
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP claimed
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent SYMRISE AG (DE) 2026-02-12 US claimed
US-20260041095-A1 A PRESERVATION METHOD ANALYTICON DISCOVERY ZWEIGNIEDERLASSUNG DER BRAIN BIOTECH AG (DE) 2026-02-12 US claimed
US-20260034044-A1 A PRESERVATIVE COMPOSITION ANALYTICON DISCOVERY ZWEIGNIEDERLASSUNG DER BRAIN BIOTECH AG (DE) 2026-02-05 US claimed
EP-0627908-A1 COMPOSITIONS SMITHKLINE BEECHAM PLC (GB) 1994-12-14 EP claimed
WO-1994012115-A1 PROTECTIVE MEDICAL GLOVE AND ANTIBACTERIAL/ANTIPERSPIRANT COMPOSITION FOR REDUCING BACTERIAL GROWTH DURING USE OF MEDICAL GLOVES BUCHANAN, INC. (US) 1994-06-09 WO claimed
WO-1993016681-A1 COMPOSITIONS SMITHKLINE BEECHAM PLC (GB) 1993-09-02 WO claimed
EP-0423015-B1 EFFERVESCENT NAILS COMPOSITION L'OREAL (FR) 1993-05-05 EP claimed
EP-0526473-A1 CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1993-02-10 EP claimed
WO-1993000089-A1 CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1993-01-07 WO claimed
US-5100674-A Urea, bicarbonate, pyrrolidonecarboxylic acid mixture L'OREAL (FR) 1992-03-31 US claimed
WO-1991017237-A1 CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1991-11-14 WO claimed
EP-0422803-A2 Dentifrice comprising cationic antibacterial agent Beecham Group p.l.c. (GB) 1991-04-17 EP claimed
EP-0049177-B1 DRESSING COMPRISING A TEXTILE BASE ASSOCIATED WITH A DERMATOLOGICAL COMPOSITION CONTAINING AN ENZYME AND PROCESS FOR ITS PREPARATION LABORATOIRES D'HYGIENE ET DE DIETETIQUE L.H.D. Société Anonyme dite: (FR) 1984-01-18 EP claimed