Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.57 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14458827 | 1.00 | CCR2 (0.57) | CCR2CCR5 | |
| SCHEMBL14100841 | 0.84 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL14599227 | 0.84 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL14599228 | 0.84 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL4821868 | 0.81 | CCR2 (0.57) | CCR2CCR5 | |
| SCHEMBL14458770 | 0.79 | CCR2 (0.55) | CCR2CCR5 | |
| SCHEMBL14011028 | 0.75 | CCR2 (0.63) | CCR2CCR5 | |
| SCHEMBL18901543 | 0.75 | CCR2 (0.63) | CCR2CCR5 | |
| SCHEMBL3326857 | 0.75 | CCR2 (0.63) | CCR2CCR5 | |
| SCHEMBL14169517 | 0.74 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155731-A1 | Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155731-A1 | Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity | CCR2, ACKR3, CCR7 | CCR2 1/4885CCR5 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.