Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26978909 | 0.90 | SYK (0.53) | SYKMAPTCTRB1PPARACTSK | |
| SCHEMBL27125801 | 0.90 | SYK (0.53) | SYKMAPTCTRB1PPARACTSK | |
| SCHEMBL116302 | 0.89 | SYK (0.46) | SYKCTRB1CTSKCTSSCTSL | |
| SCHEMBL5724195 | 0.88 | SYK (0.52) | SYKCTRB1CTSKCTSSCTSL | |
| SCHEMBL263992 | 0.87 | SYK (0.47) | SYKCTRB1CTSKCTSSCTSL | |
| SCHEMBL31316318 | 0.85 | ATM (0.42) | SYKMAPTPPARACTSKCTSS | |
| SCHEMBL1555741 | 0.84 | SYK (0.57) | SYKMAPTCTRB1PPARACTSK | |
| SCHEMBL1555742 | 0.84 | SYK (0.57) | SYKMAPTCTRB1PPARACTSK | |
| SCHEMBL5724356 | 0.84 | SYK (0.49) | SYKCTRB1CTSKCTSSCTSL | |
| SCHEMBL5724348 | 0.84 | SYK (0.57) | SYKCTRB1CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | SYK 4291/4885MAPT 4835/4885CTRB1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.