SCHEMBL14479727

SCHEMBL14479727

IC(c1ccccc1)C1C=CC=CC1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12199461 0.78 CYP3A4 (0.38) SIGMAR1
SCHEMBL21165081 0.78 EPHX1 (0.38)
SCHEMBL3469048 0.76 DPP4 (0.45) SIGMAR1
SCHEMBL13077266 0.76 DPP4 (0.45) SIGMAR1
SCHEMBL14627615 0.76 DPP4 (0.45) SIGMAR1
SCHEMBL2738406 0.74 KDM4E (0.43)
SCHEMBL12637382 0.74 GPR84 (0.33)
SCHEMBL20311848 0.74 AOC3 (0.33)
SCHEMBL9921489 0.74 CHRNB4 (0.41)
SCHEMBL21554360 0.73 DPP4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325213-B1 CATALYST FOR LIVING RADICAL POLYMERIZATION UNIV KYOTO (JP) 2013-01-02 EP disclosed