SCHEMBL1448030

SCHEMBL1448030

C=C(C)C(=O)OCC(CC)CCCC.C=CC(=O)OCCCC

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.70
HPGD P15428 1/20 0.56
CYP3A4 P08684 5/20 0.47
ATM Q13315 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 5/20 0.42
CA2 P00918 1/20 0.42
RECQL P46063 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
LMNA P02545 3/20 0.40
MAPK1 P28482 2/20 0.40
HSD17B10 Q99714 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066521 0.95 TSHR (0.67) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL9766284 0.95 TSHR (0.67) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL4901912 0.95 TSHR (0.74) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL9065069 0.93 TSHR (0.81) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL10477292 0.93 TSHR (0.67) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL9227581 0.92 TSHR (0.66) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL10773417 0.92 TSHR (0.66) TSHRHPGDCYP3A4ATMTDP1
Ethylene Glycol SCHEMBL6060432 0.91 TSHR (0.65) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL5059316 0.91 TSHR (0.69) TSHRHPGDCYP3A4ATMTDP1
SCHEMBL6849095 0.91 TSHR (0.69) TSHRHPGDCYP3A4ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3470455-B1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME SHINETSU CHEMICAL CO (JP) 2020-11-04 EP claimed
EP-3470455-A1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2019-04-17 EP claimed
US-6450675-B1 MIXTURE OF POLYMER AND ANTISTATIC AGENT KANEKA CORP. (JP) 2002-09-17 US claimed
US-11613639-B2 Polyvinyl chloride-based resin molded product and method for manufacturing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-28 US disclosed
CN-105264012-B Rubber-reinforced thermoplastic resin composition and resin molded article 日本A&L株式会社 2021-02-19 CN disclosed
EP-3470455-B1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME SHINETSU CHEMICAL CO (JP) 2020-11-04 EP disclosed
US-10717860-B2 Polyvinyl chloride-based resin molded product and method for manufacturing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-21 US disclosed
US-20190112464-A1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-04-18 US disclosed
US-20190112463-A1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-04-18 US disclosed
EP-3470455-A1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2019-04-17 EP disclosed
EP-3470609-A1 POLYVINYL CHLORIDE-BASED RESIN MOLDED PRODUCT AND METHOD FOR MANUFACTURING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2019-04-17 EP disclosed
US-20040249069-A1 Resin composition for direct vapor deposition, molded articles made by using the same, and surface-metallized lamp housing MITSUBISHI RAYON CO., LTD. (JP) 2004-12-09 US disclosed
EP-1101799-B1 IMPACT-RESISTANT THERMOPLASTIC RESIN COMPOSITION KANEKA CORP (JP) 2004-10-27 EP disclosed
EP-1445281-A1 RESIN COMPOSITION FOR DIRECT VAPOR DEPOSITION MOLDED ARTICLES MADE BY USING THE SAME AND SURFACE METALLIZED LAMP HOUSING Mitsubishi Rayon Co., Ltd. (JP) 2004-08-11 EP disclosed
EP-1394217-A2 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
US-6450675-B1 MIXTURE OF POLYMER AND ANTISTATIC AGENT KANEKA CORP. (JP) 2002-09-17 US disclosed
US-6335399-B1 LOW IN RIGIDITY, TENSILE STRENGTH, DUCTILITY, MOLDED PRODUCT SHOWS NO SHARP EDGE ON RUPTURE CROSS-SECTION UPON COLLISION, HAS A HIGH RESISTANCE TO THERMAL DEFORMATION AND EXHIBITS AN EXCELLENT MOLDABILITY. KANEKA CORPORATION (JP) 2002-01-01 US disclosed
US-6306961-B1 Thermoplastic resin composition having impact resistance KANEKA CORPORATION (JP) 2001-10-23 US disclosed
EP-1101799-A1 IMPACT-RESISTANT THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2001-05-23 EP disclosed
EP-0978539-A1 IMPACT-RESISTANT THERMOPLASTIC RESIN COMPOSITION KANEKA CORPORATION (JP) 2000-02-09 EP disclosed