Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708767 | 0.95 | TSHR (0.67) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL30200835 | 0.95 | TSHR (0.71) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL10797039 | 0.95 | TSHR (0.71) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL1823127 | 0.95 | TSHR (0.71) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL1448030 | 0.95 | TSHR (0.70) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL10773417 | 0.94 | TSHR (0.66) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL11407971 | 0.94 | TSHR (0.69) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL6849095 | 0.94 | TSHR (0.69) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL9065069 | 0.93 | TSHR (0.81) | TSHRHPGDCYP3A4TDP1ATM | |
| SCHEMBL11385705 | 0.93 | TSHR (0.62) | TSHRHPGDCYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082227-A1 | Transdermal device comprising a reservoir and a matrix containing the same active principle | PIERRE FABRE MEDICAMENT (FR) | 2003-05-01 | — | — | US | claimed |
| JP-5230318-A | — | — | None | — | — | JP | disclosed |
| US-20080057810-A1 | Production Of Absorbent Composites | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20030082227-A1 | Transdermal device comprising a reservoir and a matrix containing the same active principle | PIERRE FABRE MEDICAMENT (FR) | 2003-05-01 | — | — | US | disclosed |
| US-6254751-B1 | Process for the multi-layered coating of substrates with electrophoretic coating material and powder coating material | BASF COATINGS AG (DE) | 2001-07-03 | — | — | US | disclosed |
| JP-H05230318-A | THERMOSETTING RESIN COMPOSITION | KANEGAFUCHI CHEM IND CO LTD | 1993-09-07 | — | — | JP | disclosed |
| US-4962165-A | Process for making silicone particles | ROHM AND HAAS COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0378370-A2 | Process for making silicone-containing polymer particles | ROHM AND HAAS COMPANY (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4293661-A | GLYCIDYL ACRYLATE, GLYCIDYL VINYL ETHER | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-3988405-A | CERAMIC, ACRYLIC POLYMER BINDER | SMITH ROBERT D | 1976-10-26 | — | — | US | disclosed |