Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 12/20 | 0.59 |
| ▸ | KDR | P35968 | 6/20 | 0.49 |
| ▸ | BRAF | P15056 | 5/20 | 0.49 |
| ▸ | RET | P07949 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012882 | 0.88 | RAF1 (0.66) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL14481187 | 0.87 | RAF1 (0.59) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL694648 | 0.85 | RAF1 (0.67) | RAF1KDRBRAFRETEPHX2 | |
| Hydrochloric Acid SCHEMBL1702120 | 0.85 | RAF1 (0.66) | RAF1KDRBRAFRETEPHX2 | |
| Hydrochloric Acid SCHEMBL1702492 | 0.84 | RAF1 (0.65) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL16143280 | 0.83 | RAF1 (0.68) | RAF1KDRBRAFRETEPHX2 | |
| Sulfuric Acid SCHEMBL2043327 | 0.82 | RAF1 (0.63) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL1702479 | 0.82 | RAF1 (0.63) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL26239025 | 0.81 | RAF1 (0.70) | RAF1KDRBRAFRETEPHX2 | |
| SCHEMBL14480612 | 0.81 | RAF1 (0.88) | RAF1KDRBRAFRETEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012548-A1 | DEUTERIUM-SUBSTITUTED OMEGA-DIPHENYLUREA AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD. (CN) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012548-A1 | DEUTERIUM-SUBSTITUTED OMEGA-DIPHENYLUREA AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | PPARD, HDHD5, SCD | RAF1 2908/4885KDR 1916/4885BRAF 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.