Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081285 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL30353758 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL31451989 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL20298750 | 0.84 | NPC1 (0.50) | ALDH1A1MAPTLMNANPC1POLB | |
| SCHEMBL28306231 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL4196549 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL13987139 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL12548246 | 0.83 | MAPT (0.44) | ALDH1A1MAPTLMNAHTTNPC1 | |
| SCHEMBL25249572 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL3720610 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008791-A1 | CHEMICAL COMPOUNDS | BORAH INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-12358932-B2 | Chemical compounds | BORAH, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| CN-119731169-A | Sodium channel regulator and application thereof | 上海汇伦医药股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240368196-A1 | CHEMICAL COMPOUNDS | BORAH, INC. | 2024-11-07 | — | — | US | disclosed |
| CN-114341145-B | Chemical compound | 博拉公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2024046253-A1 | SODIUM CHANNEL REGULATOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| CN-117242080-A | Boron-containing pyrazole compounds, compositions comprising the same, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2023-12-15 | — | — | CN | disclosed |
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2022133420-A1 | BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-06-23 | — | — | WO | disclosed |
| US-7910585-B2 | Pyrimidine derivatives | NOVARTIS AG (CH) | 2011-03-22 | — | — | US | disclosed |
| US-7910585-B2 | Pyrimidine derivatives | NOVARTIS AG (CH) | 2011-03-22 | — | — | US | disclosed |
| WO-2011025565-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-03 | — | — | WO | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |
| US-20080293708-A1 | Pyrimidine Derivatives | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| US-20080293708-A1 | Pyrimidine Derivatives | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| US-20080293708-A1 | Pyrimidine Derivatives | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| CN-101006079-A | Pyrimidine derivatives | NOVARTIS AG (CH) | 2007-07-25 | — | — | CN | disclosed |
| EP-1784399-A2 | PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021457-A2 | PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008791-A1 | CHEMICAL COMPOUNDS | JAK3, JAK2, JAK1 | ALDH1A1 2401/4885MAPT 4400/4885LMNA 4610/4885 |
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | JAK3, JAK1, JAK2 | ALDH1A1 3977/4885MAPT 2548/4885LMNA 4698/4885 |
| US-20240368196-A1 | CHEMICAL COMPOUNDS | PDE4A, PDE4B, SYK | ALDH1A1 2613/4885MAPT 2233/4885LMNA 4874/4885 |
| US-20080293708-A1 | Pyrimidine Derivatives | DPYD, TYMP, TYMS | ALDH1A1 955/4885MAPT 2574/4885LMNA 3279/4885 |
| US-12358932-B2 | Chemical compounds | PDE4A, PDE4B, SYK | ALDH1A1 2613/4885MAPT 2233/4885LMNA 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.