Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261133 | 1.00 | LMNA (0.64) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL27697998 | 1.00 | LMNA (0.64) | LMNAGAAMEN1KMT2AHDAC3 | |
| Trifluoroacetic Acid SCHEMBL29494217 | 0.92 | HDAC3 (0.63) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL14407769 | 0.91 | LMNA (0.61) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL11830073 | 0.91 | LMNA (0.61) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL30083276 | 0.90 | LMNA (0.57) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL11839536 | 0.90 | NPC1 (0.62) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL1319920 | 0.90 | LMNA (0.60) | LMNAGAAMEN1KMT2AHDAC3 | |
| SCHEMBL11830818 | 0.90 | LMNA (0.60) | LMNAGAAMEN1KMT2AHDAC3 | |
| Hydrochloric Acid SCHEMBL10526889 | 0.88 | LMNA (0.59) | LMNAGAAMEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101072745-A | Novel diazaphospholane ligands for asymmetric catalysis | DOW CHEMICAL CO (US) | 2007-11-14 | — | — | CN | disclosed |
| US-7235283-B2 | Optical compensation plate and deflecting plate using the same | NITTO DENKO CORPORATION (JP) | 2007-06-26 | — | — | US | disclosed |
| US-7235283-B2 | Optical compensation plate and deflecting plate using the same | NITTO DENKO CORPORATION (JP) | 2007-06-26 | — | — | US | disclosed |