Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123617 | 0.85 | GFER (0.50) | NPY5RMEN1KMT2AMCHR1ALDH1A1 | |
| SCHEMBL785159 | 0.82 | F10 (0.51) | NPY5RLSSF10USP2 | |
| SCHEMBL5158523 | 0.81 | NPY5R (0.45) | NPY5RNOTUMLSSMCHR1F10 | |
| SCHEMBL27629490 | 0.81 | NPY5R (0.46) | NPY5RUSP2 | |
| SCHEMBL5536857 | 0.81 | NPY5R (0.52) | NPY5RNOTUMLSSMEN1KMT2A | |
| SCHEMBL3593317 | 0.79 | SIGMAR1 (0.55) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL9451762 | 0.79 | HTR2A (0.51) | LSSMEN1KMT2AMCHR1ALDH1A1 | |
| Fumaric Acid SCHEMBL9451757 | 0.79 | HTR2A (0.51) | LSSMEN1KMT2AMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3592267 | 0.78 | SIGMAR1 (0.54) | LSS | |
| SCHEMBL16422987 | 0.77 | NOTUM (0.58) | NPY5RNOTUMMCHR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |