Asparagine

Asparagine

SCHEMBL14486115

C[C@@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
SLC1A1 P43005 4/20 0.50
GRIK1 P39086 10/20 0.48
GRIK2 Q13002 5/20 0.48
GRIA4 P48058 3/20 0.48
GRIK3 Q13003 3/20 0.48
GRIK5 Q16478 3/20 0.48
GRIA2 P42262 2/20 0.48
GRIA1 P42261 1/20 0.48
ALOX15 P16050 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
KMT2A Q03164 1/20 0.48
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL286919 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL286918 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL18696151 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL8318136 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL7325420 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL14486114 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL8318140 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL28219869 0.96 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL28837862 0.92 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL9395845 0.92 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2729570-A2 REAGENT USABLE FOR THE ISOLATION AND/OR PURIFICATION OF NUCLEIC ACIDS Qiagen GmbH (DE) 2014-05-14 EP disclosed
WO-2013004710-A2 REAGENT USABLE FOR THE ISOLATION AND/OR PURIFICATION OF NUCLEIC ACIDS QIAGEN GMBH (DE) 2013-01-10 WO disclosed