Asparagine

Asparagine

SCHEMBL286918

CC(N)C(=O)O.NC(=O)CC(N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
SLC1A1 P43005 4/20 0.50
GRIK1 P39086 10/20 0.48
GRIK2 Q13002 5/20 0.48
GRIA4 P48058 3/20 0.48
GRIK3 Q13003 3/20 0.48
GRIK5 Q16478 3/20 0.48
GRIA2 P42262 2/20 0.48
GRIA1 P42261 1/20 0.48
ALOX15 P16050 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
KMT2A Q03164 1/20 0.48
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL286919 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL18696151 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL8318136 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL7325420 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL14486114 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL8318140 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL14486115 1.00 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL28219869 0.96 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL28837862 0.92 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Asparagine SCHEMBL9395845 0.92 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122440-B1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS KAO GERMANY GMBH (DE) 2024-04-03 EP disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
CN-115844896-A Methods of treating arenaviridae and coronaviridae virus infections 吉利德科学公司 2023-03-28 CN disclosed
EP-3279323-B1 AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY KIKKOMAN CORP (JP) 2023-03-08 EP disclosed
US-10934530-B2 Amadoriase having improved specific activity KIKKOMAN CORPORATION (JP) 2021-03-02 US disclosed
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2021-02-11 US disclosed
EP-3737420-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2020-11-18 EP disclosed
EP-3694646-A1 A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM Metabolon, Inc. (US) 2020-08-19 EP disclosed
US-10369091-B2 Core shell silica particles and uses thereof as an anti-bacterial agent COLGATE-PALMOLIVE COMPANY (US) 2019-08-06 US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
WO-2019074757-A1 A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM METABOLON, INC. (US) 2019-04-18 WO disclosed
US-20180371429-A1 AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY KIKKOMAN CORPORATION (JP) 2018-12-27 US disclosed
EP-3279323-A1 AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY Kikkoman Corporation (JP) 2018-02-07 EP disclosed
US-20160338920-A1 CORE SHELL SILICA PARTICLES AND USES THEREOF AS AN ANTI-BACTERIAL AGENT COLGATE PALMOLIVE CO (US) 2016-11-24 US disclosed
EP-2427775-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS BCN Peptides, S.A. (ES) 2012-03-14 EP disclosed
WO-2010128098-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS BCN PEPTIDES, S.A. (ES) 2010-11-11 WO disclosed
CN-1895066-A Anti-body leben tablet (powder) GOU CHUNHU (CN) 2007-01-17 CN disclosed
US-5747050-A COSMETICS WITH SODIUM CHLORIDE AND PEAT TORF ESTABLISHMENT (LI) 1998-05-05 US disclosed
US-5428171-A Leukotrienes antagonist; antiasthmatic, antiallergic, anti-inflammatory and cytoprotective agent MERCK FROSST CANADA, INC. (CA) 1995-06-27 US disclosed
US-5112808-A Promotes release of growth hormone AMERICAN CYANAMID COMPANY (US) 1992-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338920-A1 CORE SHELL SILICA PARTICLES AND USES THEREOF AS AN ANTI-BACTERIAL AGENT SRI, CAPG, SAE1 SLC7A5 1816/4885SLC1A3 3772/4885SLC1A2 4124/4885
US-10369091-B2 Core shell silica particles and uses thereof as an anti-bacterial agent SRI, CAPG, SAE1 SLC7A5 1816/4885SLC1A3 3772/4885SLC1A2 4124/4885
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 SLC7A5 1891/4885SLC1A3 3392/4885SLC1A2 3978/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 SLC7A5 1891/4885SLC1A3 3392/4885SLC1A2 3978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.