Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485801 | 0.91 | CFTR (0.32) | EPHA2KDREPHB4SOS1GRIN2B | |
| SCHEMBL14485837 | 0.88 | KDR (0.41) | EPHA2KDREPHB4P2RX7TP53 | |
| SCHEMBL14486246 | 0.85 | PIP4K2A (0.38) | TP53 | |
| SCHEMBL14486540 | 0.85 | MAPT (0.34) | EPHA2KDREPHB4 | |
| SCHEMBL14485965 | 0.85 | LMNA (0.35) | EPHA2KDREPHB4TP53 | |
| SCHEMBL14485948 | 0.84 | CNR2 (0.33) | EPHA2KDREPHB4P2RX7 | |
| SCHEMBL14485991 | 0.82 | MAPT (0.41) | EPHA2KDREPHB4TP53 | |
| SCHEMBL12477392 | 0.82 | EGFR (0.39) | EGFREPHA2KDREPHB4GRIN2B | |
| SCHEMBL12476504 | 0.82 | EPHA2 (0.36) | EPHA2KDREPHB4P2RX7 | |
| SCHEMBL12476997 | 0.81 | EGFR (0.39) | EGFREPHA2KDREPHB4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006442-B2 | Cannabinoid receptor modulators | LUPIN LIMITED (IN) | 2015-04-14 | — | — | US | claimed |
| WO-2013005168-A2 | CANNABINOID RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2013-01-10 | — | — | WO | claimed |