SCHEMBL14486385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14554958	0.90	CLK4 (0.47)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL14554917	0.90	CLK4 (0.44)	VNN1CLK4DYRK1ACYP1A2CYP3A4
	SCHEMBL14486099	0.88	CLK4 (0.51)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL14554930	0.87	CLK4 (0.50)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL15935057	0.85	CLK4 (0.45)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL14554915	0.83	CLK4 (0.54)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL14554837	0.82	HDAC3 (0.46)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL15918511	0.82	VNN1 (0.48)	VNN1CLK4DYRK1ALMNAALDH1A1
	SCHEMBL14554957	0.81	CLK4 (0.48)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6
	SCHEMBL14486039	0.81	CLK4 (0.50)	CLK4DYRK1ACYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.