SCHEMBL14487563

SCHEMBL14487563

CCC(C)(C)C(=O)OCCC1C2CC3CC(C2)CC1C3

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.37
HMGCR P04035 4/20 0.33
EPHX2 P34913 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
EPHX1 P07099 1/20 0.31
FKBP1A P62942 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20411147 0.80 HSD11B1 (0.32) HSD11B1
SCHEMBL11946890 0.79 HSD11B1 (0.35) HSD11B1HMGCREPHX2L3MBTL1EPHX1
SCHEMBL16744375 0.78 EPHX2 (0.37) HSD11B1HMGCREPHX2L3MBTL1FKBP1A
SCHEMBL10259392 0.77 HSD11B1 (0.31) HSD11B1
SCHEMBL11948956 0.77 HSD11B1 (0.36) HSD11B1EPHX2L3MBTL1EPHX1FKBP1A
SCHEMBL47501 0.76 HSD11B1 (0.33) HSD11B1HMGCREPHX2L3MBTL1EPHX1
SCHEMBL25516650 0.76 HMGCR (0.37) HMGCRFKBP1A
SCHEMBL17052474 0.75 HSD11B1 (0.30) HSD11B1
SCHEMBL11948965 0.75 HSD11B1 (0.34) HSD11B1EPHX2EPHX1FKBP1A
SCHEMBL17735912 0.74 HSD11B1 (0.36) HSD11B1EPHX2L3MBTL1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7232641-B2 Polymerizable compound, polymer, positive-resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-06-19 US disclosed