SCHEMBL1448809

SCHEMBL1448809

NN([C]=O)c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
ALDH1A1 P00352 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 1/20 0.38
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5113337 0.80 CYP2D6 (0.42) CYP2D6CYP2C19NOS3NOS1NOS2
SCHEMBL316609 0.77 CYP2D6 (0.48) CYP2D6CYP2C19ALDH1A1NPC1RAB9A
SCHEMBL3127282 0.77 CYP2D6 (0.47) CYP2D6CYP2C19NOS3NOS1NOS2
SCHEMBL9183264 0.75 ALDH1A1 (0.44) CYP2D6CYP2C19ALDH1A1NPC1RAB9A
Hydrochloric Acid SCHEMBL8742974 0.75 CYP2D6 (0.45) CYP2D6CYP2C19NOS3NOS1NOS2
SCHEMBL1515667 0.73
SCHEMBL406585 0.73
SCHEMBL29678128 0.73
SCHEMBL2217230 0.73
SCHEMBL28205435 0.72 CYP2D6 (0.40) CYP2D6CYP2C19NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1887416-B1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS INC (JP) 2015-09-02 EP disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed
EP-1887416-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-13 EP disclosed
US-7153645-B2 Silver salt photo-thermal photographic dry imaging material, an image recording method and an image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-12-26 US disclosed
US-20050032010-A1 Silver salt photo-thermal photographic dry imaging material, an image recording method and an image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-02-10 US disclosed
EP-1505436-A1 A silver salt photothermographic dry imaging material Konica Minolta Medical & Graphic, Inc. (JP) 2005-02-09 EP disclosed
EP-0171217-B1 FUSED-RING HETEROCYCLIC COMPOUNDS A PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE SANKYO COMPANY LIMITED (JP) 1989-05-03 EP disclosed
US-4716162-A BRAIN FUNCTION SANKYO COMPANY, LIMITED (JP) 1987-12-29 US disclosed
EP-0171217-A2 Fused-ring heterocyclic compounds a process for their production and their pharmaceutical use SANKYO COMPANY LIMITED (JP) 1986-02-12 EP disclosed