⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibromomethane SCHEMBL20701 | 0.77 | — | — | |
| SCHEMBL2289057 | 0.76 | — | — | |
| SCHEMBL4354048 | 0.76 | — | — | |
| SCHEMBL13992311 | 0.76 | — | — | |
| SCHEMBL3761033 | 0.76 | — | — | |
| Bromoethanamine SCHEMBL12391152 | 0.72 | — | — | |
| 2-Bromoethanol SCHEMBL13916048 | 0.72 | — | — | |
| SCHEMBL18806904 | 0.67 | — | — | |
| Bromoethane SCHEMBL703294 | 0.67 | — | — | |
| SCHEMBL1330193 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981686-A | Preparation method and preparation device of 1,1,2, 2-tetradeuteroethylene | 中国船舶重工集团公司第七一八研究所 | 2020-04-10 | — | — | CN | claimed |
| US-12552790-B2 | Positive modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2026-02-17 | — | — | US | disclosed |
| US-20260035366-A1 | POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2026-02-05 | — | — | US | disclosed |
| US-12448380-B2 | Positive modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| US-12344608-B2 | Positive modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2025-07-01 | — | — | US | disclosed |
| WO-2025103493-A1 | CANNABINOID RECEPTOR 1 ANTAGONIST AND USE THEREOF | 西藏海思科制药有限公司 | 2025-05-22 | — | — | WO | disclosed |
| CN-116209446-B | 7- (Piperidin-1-yl) -4H-pyrimido [1,2-B ] pyridazin-4-one derivatives as positive allosteric modulators of muscarinic acetylcholine receptor M4 | 范德堡大学 | 2025-05-13 | — | — | CN | disclosed |
| US-20250136600-A1 | POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2025-05-01 | — | — | US | disclosed |
| US-20250122199-A1 | POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2025-04-17 | — | — | US | disclosed |
| US-20100076010-A1 | ALPHA 1A-ADRENOCEPTOR ANTAGONISTS | CONCERT PHARMACEUTICALS, INC. | 2010-03-25 | — | — | US | disclosed |
| US-20100076010-A1 | ALPHA 1A-ADRENOCEPTOR ANTAGONISTS | CONCERT PHARMACEUTICALS, INC. | 2010-03-25 | — | — | US | disclosed |
| US-20100016365-A1 | SUBSTITUTED 4-AMINO-PIPERIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| EP-2125717-A2 | DEUTERATED DERIVATIVES OF SILODOSIN AS ALPHA IA-ADRENORECEPTOR ANTAGONISTS | Concert Pharmaceuticals Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-20090062374-A1 | DEUTERIUM-ENRICHED LASOFOXIFENE | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090012112-A1 | Alpha 1A-adrenoceptor antagonists | CONCERT PHARMACEUTICALS, INC. | 2009-01-08 | — | — | US | disclosed |
| US-20090012112-A1 | Alpha 1A-adrenoceptor antagonists | CONCERT PHARMACEUTICALS, INC. | 2009-01-08 | — | — | US | disclosed |
| WO-2008106125-A2 | DEUTERATED DERIVATIVES OF SILODOSIN AS ALPHA LA-ADRENOCEPTOR ANTAGONISTS | CONCERT PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20080051422-A1 | 4-Aminoquinazoline derivatives and methods of use thereof | CONCERT PHARMACEUTICALS INC. (US) | 2008-02-28 | — | — | US | disclosed |
| US-7157284-B2 | Vacuum distillation automatic sampler | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ENVIRONMENTAL PROTECTION AGENCY (US) | 2007-01-02 | — | — | US | disclosed |