⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dibromoethane SCHEMBL1448860 | 0.77 | — | — | |
| SCHEMBL18806904 | 0.72 | — | — | |
| Bromoethane SCHEMBL703294 | 0.72 | — | — | |
| 1,2-Dibromoethane SCHEMBL11411440 | 0.72 | — | — | |
| SCHEMBL1330193 | 0.72 | — | — | |
| SCHEMBL4354048 | 0.68 | — | — | |
| SCHEMBL13992311 | 0.68 | — | — | |
| SCHEMBL2289057 | 0.68 | — | — | |
| SCHEMBL95676 | 0.68 | — | — | |
| SCHEMBL13916373 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228590-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2014-08-14 | — | — | US | claimed |
| EP-2748134-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | Piramal Imaging SA (CH) | 2014-07-02 | — | — | EP | claimed |
| WO-2013026941-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2013-02-28 | — | — | WO | claimed |
| US-20150196544-A1 | NOVEL BENZO[d][1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS, INC. | 2015-07-16 | — | — | US | disclosed |
| US-20140296566-A1 | Simplified Radiosynthesis of O-[18F]Fluoromethyl Tyrosine Derivatives | PIRAMAL IMAGING SA (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140228590-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2014-08-14 | — | — | US | disclosed |
| EP-2748140-A1 | SIMPLIFIED RADIOSYNTHESIS OF O-[18F]FLUOROMETHYL TYROSINE DERIVATIVES | Piramal Imaging SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| EP-2748134-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | Piramal Imaging SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-20140018390-A1 | DEUTERATED BENZO[D][1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8450492-B2 | Deuterated benzo[D][1,3]-dioxol derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2013-05-28 | — | — | US | disclosed |
| WO-2013026940-A1 | SIMPLIFIED RADIOSYNTHESIS OF O-[18F]FLUOROMETHYL TYROSINE DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-02-28 | — | — | WO | disclosed |
| EP-1910322-A2 | NOVEL BENZO [D][1,3]-DIOXOL DERIVATIVES | Concert Pharmaceuticals Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1909576-A2 | NOVEL PHARMACEUTICAL COMPOUNDS | Concert Pharmaceuticals Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080033011-A1 | NOVEL BENZO[D][1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2008-02-07 | — | — | US | disclosed |
| US-20070191432-A1 | Novel benzo[D][1,3]-dioxol derivatives | CONCERT PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191381-A1 | Novel pharmaceutical compounds | CONCERT PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070037815-A1 | Novel pharmaceutical compounds | CONCERT PHARMACEUTICALS, INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2007016431-A2 | NOVEL BENZO [D] [1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016361-A2 | NOVEL PHARMACEUTICAL COMPOUNDS | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| US-4226808-A | 1-Aryl-2-dihalogenodeuterioalkanoylamido-1,3-propanediol antibacterial agents | SCHERING CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |