Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | PER2 | O15055 | 8/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594212 | 0.82 | PIK3CD (0.55) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31443583 | 0.77 | — | — | |
| SCHEMBL14749920 | 0.77 | — | — | |
| SCHEMBL14749923 | 0.77 | — | — | |
| SCHEMBL868824 | 0.77 | — | — | |
| SCHEMBL6258023 | 0.76 | CYP3A4 (0.45) | PIK3CD | |
| SCHEMBL10392279 | 0.75 | — | — | |
| SCHEMBL13069654 | 0.75 | — | — | |
| SCHEMBL13631976 | 0.74 | PER2 (0.46) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20894926 | 0.73 | PIK3CD (0.58) | PIK3CDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235544-B2 | for use in conjunction with thrombolytic agents, thus permitting the use of a lower dose of thrombolytic agent; treatment of acute vascular diseases; may have potential in neurogenerative diseases such as Parkinson's and Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-06-26 | — | — | US | disclosed |