SCHEMBL14489609

SCHEMBL14489609

O=C1C=CC(=O)C2=C1CCN2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.39
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCZ Q05513 1/20 0.32
PRKCD Q05655 1/20 0.32
PRKD1 Q15139 1/20 0.32
USP7 Q93009 1/20 0.32
USP21 Q9UK80 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11620338 0.70 CRBN (0.43) CRBN
SCHEMBL17416816 0.67 CRBN (0.35) CRBN
SCHEMBL973342 0.67 CDC25B (0.39)
SCHEMBL5398290 0.63 CRBN (0.41) CRBNPRKD3PRKCGPRKCBPRKCA
SCHEMBL591093 0.62 CDC25B (0.48)
SCHEMBL4981136 0.62 CDC25B (0.42) CRBN
SCHEMBL2585200 0.60
SCHEMBL42430 0.59
SCHEMBL14570100 0.58 CRBN (0.35) CRBN
SCHEMBL24447537 0.57 PARP10 (0.33) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070138060-A1 Upgrading of peroxide treated petroleum streams EXXONMOBIL RESEARCH & ENGINEERING CO. 2007-06-21 US disclosed
US-20070138060-A1 Upgrading of peroxide treated petroleum streams EXXONMOBIL RESEARCH & ENGINEERING CO. 2007-06-21 US disclosed
US-20070140949-A1 Extraction of peroxide treated petroleum streams EXXONMOBIL RESEARCH & ENGINEERING CO. 2007-06-21 US disclosed
US-20070140949-A1 Extraction of peroxide treated petroleum streams EXXONMOBIL RESEARCH & ENGINEERING CO. 2007-06-21 US disclosed