Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489791 | 0.88 | MCHR1 (0.66) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14489799 | 0.85 | MCHR1 (0.64) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14489806 | 0.84 | MCHR1 (0.72) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14500218 | 0.83 | MCHR1 (0.61) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14489861 | 0.82 | MCHR1 (0.60) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14500565 | 0.82 | MCHR1 (0.60) | MCHR1ACHECTNNB1WNT3AHTT | |
| SCHEMBL14489855 | 0.81 | MCHR1 (0.59) | MCHR1ACHECTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL14489793 | 0.81 | MCHR1 (0.68) | MCHR1ACHECTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL14489792 | 0.81 | MCHR1 (0.59) | MCHR1ACHECTNNB1WNT3ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5422955 | 0.81 | MCHR1 (0.58) | MCHR1ACHECTNNB1WNT3AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |