Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493231 | 0.90 | KDM4E (0.43) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2837220 | 0.88 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2834800 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL14493314 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2838033 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2838757 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2833141 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2838117 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2838859 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL14493287 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590352-B1 | 4-AMINOTHIENO [2,3-d] PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS | ALMIRALL LAB (ES) | 2007-06-27 | — | — | EP | disclosed |