Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19708164 | 1.00 | MEN1 (0.53) | MEN1KMT2ATAAR1EPHX1CTSS | |
| SCHEMBL19033467 | 0.84 | MEN1 (0.56) | MEN1KMT2ATAAR1EPHX1 | |
| SCHEMBL6469693 | 0.84 | MEN1 (0.56) | MEN1KMT2ATAAR1EPHX1 | |
| SCHEMBL697901 | 0.84 | EPHX1 (0.61) | MEN1KMT2ATAAR1EPHX1L3MBTL1 | |
| SCHEMBL8211678 | 0.84 | EPHX1 (0.61) | MEN1KMT2ATAAR1EPHX1L3MBTL1 | |
| SCHEMBL697900 | 0.84 | EPHX1 (0.61) | MEN1KMT2ATAAR1EPHX1L3MBTL1 | |
| Benzene SCHEMBL27636787 | 0.84 | EPHX1 (0.61) | MEN1KMT2ATAAR1EPHX1L3MBTL1 | |
| SCHEMBL22175193 | 0.84 | CYP3A4 (0.60) | MEN1KMT2ATAAR1EPHX1CTSS | |
| SCHEMBL23019169 | 0.83 | MME (0.47) | MEN1KMT2ATAAR1CTSSCTSK | |
| SCHEMBL22317109 | 0.83 | CTSS (0.52) | CTSSCTSKL3MBTL1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |