SCHEMBL14498058

SCHEMBL14498058

CC(C)C[C@H](NC(=O)[C@@H](C)Cc1ccc(Cl)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N(C)[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 18/20 0.62
▸ IL23R Q5VWK5 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14498065 1.00 KISS1R (0.62) KISS1RIL23R
SCHEMBL12417315 0.95 KISS1R (0.65) KISS1RIL23R
SCHEMBL13248723 0.95 KISS1R (0.65) KISS1RIL23R
SCHEMBL14498068 0.95 KISS1R (0.65) KISS1RIL23R
SCHEMBL14498050 0.92 IL23R (0.64) KISS1RIL23R
SCHEMBL12417309 0.92 IL23R (0.64) KISS1RIL23R
SCHEMBL13248726 0.92 KISS1R (0.66) KISS1RIL23R
SCHEMBL14498063 0.92 IL23R (0.63) KISS1RIL23R
SCHEMBL29400465 0.91 KISS1R (0.69) KISS1RIL23R
SCHEMBL12417304 0.90 KISS1R (0.59) KISS1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135351-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof CONDE-KNAPE KARIN 2007-06-14 — — US disclosed
US-20070135351-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof CONDE-KNAPE KARIN 2007-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135351-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof NPY2R, NPY1R, NPY4R KISS1R 131/4885IL23R 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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