Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694560 | 0.90 | MEN1 (0.69) | KMT2AMEN1TSHRALDH1A1POLB | |
| SCHEMBL692761 | 0.83 | L3MBTL1 (0.60) | L3MBTL1KMT2AMEN1TSHRATM | |
| SCHEMBL29595267 | 0.83 | L3MBTL1 (0.60) | L3MBTL1KMT2AMEN1TSHRATM | |
| SCHEMBL5261945 | 0.81 | TSHR (0.59) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL30866830 | 0.81 | TSHR (0.59) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL9320248 | 0.80 | KMT2A (0.59) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL30958764 | 0.79 | TSHR (0.57) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL1134878 | 0.79 | TSHR (0.57) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL12418312 | 0.79 | KMT2A (0.60) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL13311778 | 0.79 | KMT2A (0.60) | L3MBTL1KMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235548-B2 | Compounds and their use as positive AMPA receptor modulators | NEUROSEARCH A/S (DK) | 2007-06-26 | — | — | US | disclosed |