Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCND2 | P30279 | 1/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971409 | 0.89 | HDAC3 (0.59) | ALDH1A1KDM4EPDE4BPDE4DHDAC3 | |
| SCHEMBL1735195 | 0.87 | CDK1 (0.53) | ALDH1A1KDM4EPDE4BPDE4DHDAC3 | |
| SCHEMBL1735380 | 0.85 | CDK1 (0.65) | ALDH1A1PDE4BPDE4DHDAC3HDAC1 | |
| SCHEMBL1734202 | 0.85 | HDAC3 (0.50) | ALDH1A1KDM4EPDE4BPDE4DHDAC3 | |
| SCHEMBL10976137 | 0.84 | HDAC3 (0.54) | ALDH1A1KDM4EPDE4BPDE4DHDAC3 | |
| SCHEMBL14499097 | 0.84 | HDAC3 (0.54) | ALDH1A1KDM4EPDE4BPDE4DHDAC3 | |
| SCHEMBL1736454 | 0.83 | MCHR1 (0.56) | PDE4BPDE4DHDAC3HDAC1HDAC2 | |
| SCHEMBL1736584 | 0.83 | CDK1 (0.49) | PDE4BPDE4DHDAC3HDAC1HDAC2 | |
| SCHEMBL10973669 | 0.82 | ADORA2A (0.53) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4294473 | 0.81 | MCHR1 (0.54) | ALDH1A1PDE4BPDE4DHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | KIT, PRKCH, PRKCE | ALDH1A1 1472/4885KDM4E 1022/4885PDE4B 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.