Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971409 | 0.92 | HDAC3 (0.59) | CDK1KDRMEN1KMT2ANPC1 | |
| SCHEMBL14499097 | 0.86 | HDAC3 (0.54) | MEN1KMT2ANPC1RAB9AHDAC3 | |
| SCHEMBL10976137 | 0.86 | HDAC3 (0.54) | MEN1KMT2ANPC1RAB9AHDAC3 | |
| SCHEMBL13713071 | 0.85 | RAB9A (0.61) | MEN1KMT2ANPC1RAB9AHDAC3 | |
| SCHEMBL28387521 | 0.84 | MEN1 (0.51) | CDK1KDRMEN1KMT2ANPC1 | |
| SCHEMBL27739213 | 0.84 | HDAC3 (0.49) | ADORA2AADORA2BCDK1KDRMEN1 | |
| SCHEMBL13605438 | 0.84 | PIK3CG (0.51) | CDK1KDRMEN1KMT2ANPC1 | |
| SCHEMBL10973487 | 0.83 | ACHE (0.56) | CDK1KDRMEN1KMT2ANPC1 | |
| SCHEMBL1735277 | 0.83 | CSNK2A1 (0.68) | KDRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1735275 | 0.83 | RAF1 (0.59) | KDRMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | claimed |
| EP-0164204-A1 | Novel pharmaceutically useful pyrimidines | FISONS plc (GB) | 1985-12-11 | — | — | EP | claimed |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | disclosed |
| EP-0164204-A1 | Novel pharmaceutically useful pyrimidines | FISONS plc (GB) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | KIT, PRKCH, PRKCE | ADORA2A 101/4885ADORA2B 239/4885CDK1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.