Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712758 | 0.85 | KDM4E (0.64) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL16756208 | 0.84 | ALOX15 (0.59) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL1914072 | 0.83 | KDM4E (0.48) | HTTIRAK4MEN1KMT2ALMNA | |
| SCHEMBL9568812 | 0.83 | IRAK4 (0.59) | HTTIRAK4MEN1KMT2AMAPT | |
| SCHEMBL27998599 | 0.83 | IRAK4 (0.51) | HTTIRAK4MEN1KMT2AMAPT | |
| SCHEMBL12446768 | 0.82 | IRAK4 (0.58) | HTTIRAK4MEN1KMT2AMAPT | |
| SCHEMBL4084650 | 0.81 | MAPT (0.54) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL28472857 | 0.81 | IRAK4 (0.56) | HTTIRAK4MEN1KMT2AMAPT | |
| SCHEMBL28026157 | 0.81 | NPC1 (0.50) | IRAK4MEN1KMT2ALMNASLC6A3 | |
| SCHEMBL13179808 | 0.80 | IRAK4 (0.49) | HTTIRAK4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235258-B1 | Sustained-release formulations for treating CNS-mediated disorders | NPS PHARMACEUTICALS, INC. (US) | 2007-06-26 | — | — | US | disclosed |