Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.61 |
| ▸ | SPR | P35270 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412923 | 0.90 | P2RX7 (0.76) | P2RX7SPRABCB11LMNA | |
| SCHEMBL1415261 | 0.89 | P2RX7 (0.74) | P2RX7SPRABCB11LMNA | |
| SCHEMBL1412966 | 0.84 | P2RX7 (0.59) | P2RX7SPRABCB11LMNAMEN1 | |
| SCHEMBL1412881 | 0.81 | P2RX7 (0.73) | P2RX7SPRABCB11 | |
| SCHEMBL5624270 | 0.81 | P2RX7 (0.66) | P2RX7SPRABCB11 | |
| SCHEMBL1413037 | 0.79 | P2RX7 (0.57) | P2RX7SPRABCB11LMNAMEN1 | |
| SCHEMBL5623151 | 0.78 | P2RX7 (0.52) | P2RX7SPRABCB11 | |
| SCHEMBL1412885 | 0.76 | P2RX7 (1.00) | P2RX7ABCB11 | |
| SCHEMBL1412969 | 0.76 | P2RX7 (1.00) | P2RX7ABCB11 | |
| SCHEMBL1412959 | 0.76 | P2RX7 (0.58) | P2RX7SPRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235549-B2 | Benzamide, heteroarylamide and reverse amides | PFIZER INC. (US) | 2007-06-26 | — | — | US | disclosed |