SCHEMBL144995

SCHEMBL144995

CCCCCCCCOC(=O)C=CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 1.00
ATM Q13315 1/20 0.70
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
NAAA Q02083 1/20 0.52
APP P05067 3/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
PRKCA P17252 2/20 0.49
EPHX1 P07099 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1250941 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1251573 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1400161 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Fumaric Acid SCHEMBL7550623 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL8713661 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1578512 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Stearyl Fumaric Acid SCHEMBL809427 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Hexyl Fumarate SCHEMBL1419926 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1579043 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL809366 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333401-B Special material for pressure-induced resistance-change carbon nanotube modified polyolefin pipeline and preparation method thereof 山东东宏管业股份有限公司 2025-03-07 CN claimed
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
CN-118063688-A Composition for preparing oil displacement agent, oil displacement agent and preparation method of oil displacement agent 山东诺尔生物科技有限公司 2024-05-24 CN claimed
CN-117659598-A Bio-based conveyor belt covering adhesive and preparation method thereof 北京化工大学 2024-03-08 CN claimed
CN-117164760-A Functionalized fumarate/conjugated diene copolymer, preparation method thereof and bio-based elastomer 北京化工大学 2023-12-05 CN claimed
CN-115073665-B Fumarate/conjugated diene copolymer type bio-based rubber, preparation method thereof and vulcanized rubber product thereof 北京化工大学 2023-08-29 CN claimed
CN-116487599-A Functionalized conductive carbon coating aluminum current collector of power battery and preparation method thereof 湖州南木纳米科技有限公司 2023-07-25 CN claimed
EP-4200275-A2 FUMARATE DERIVATIVES AND THEIR MEDICAL USE Sitryx Therapeutics Limited (GB) 2023-06-28 EP claimed
CN-116333401-A Special material for pressure-induced resistance-change carbon nanotube modified polyolefin pipeline and preparation method thereof 山东东宏管业股份有限公司 2023-06-27 CN claimed
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-05-18 US claimed
EP-0432391-A2 Emulsion binder for carpet and carpet tiles National Starch and Chemical Investment Holding Corporation (US) 1991-06-19 EP claimed
EP-0410482-A2 Image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP claimed
US-4822676-A VINYL ESTER, ETHYLENE, ACRYLIC ESTER, MONOCARBOXYLIC ACID, TERITARY OCTYLACRYLAMIDE; PLASTICIZER RESISTANT NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1989-04-18 US claimed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
US-4753846-A COPOLYMER OF VINYL ESTER, ETHYLENE, MALEIC ACID ESTER AND MONOCARBOXYLIC ACID NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1988-06-28 US claimed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP claimed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US claimed
US-4002809-A Method of manufacturing acrylic fibers KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US claimed
US-3990980-A Hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3991226-A Method of creating an image using hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885ATM 1551/4885MAPT 4476/4885
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF F12, ACADM, ADH1A HCAR2 341/4885ATM 1551/4885MAPT 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.