Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 5/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501019 | 0.86 | PSEN1 (0.40) | F10CNR1CNR2 | |
| SCHEMBL14501016 | 0.80 | SMO (0.36) | SMO | |
| SCHEMBL2577442 | 0.80 | CA12 (0.42) | — | |
| SCHEMBL223223 | 0.79 | F10 (0.49) | F10SMOCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL221304 | 0.78 | F10 (0.48) | F10SMOCNR1CNR2 | |
| SCHEMBL16072929 | 0.74 | PSEN1 (0.38) | F10 | |
| SCHEMBL22595195 | 0.73 | EPHX1 (0.48) | — | |
| SCHEMBL10205111 | 0.73 | SMO (0.35) | SMO | |
| SCHEMBL7097824 | 0.73 | CA12 (0.39) | — | |
| SCHEMBL8186666 | 0.73 | CA12 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223738-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223738-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2007-05-29 | — | — | US | disclosed |