Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | HTR7 | P34969 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 4/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL221304 | 0.98 | F10 (0.48) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL222294 | 0.85 | F10 (0.46) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL13102745 | 0.83 | F10 (0.49) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL220468 | 0.81 | F10 (0.48) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL10218749 | 0.80 | F10 (0.46) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL2577442 | 0.80 | CA12 (0.42) | — | |
| SCHEMBL14501014 | 0.79 | F10 (0.32) | F10SMOCNR1CNR2 | |
| SCHEMBL3872404 | 0.77 | F10 (0.50) | F10ALDH1A1HRH3CYP2D6 | |
| SCHEMBL220476 | 0.74 | F10 (0.45) | F10HTR1AHTR7ALDH1A1KDM1A | |
| SCHEMBL19176641 | 0.74 | F10 (0.42) | F10HTR1AALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |