Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TYMP | P19971 | 3/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501079 | 0.99 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14501038 | 0.91 | ALDH1A1 (0.63) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14501117 | 0.88 | ALDH1A1 (0.64) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14501146 | 0.87 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14501134 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14884635 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL12395247 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21540015 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL25057498 | 0.79 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21417219 | 0.78 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214710-B2 | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214710-B2 | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |