Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.69 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982867 | 0.83 | HTR7 (0.98) | HTR7HTR1A | |
| SCHEMBL8980005 | 0.83 | HTR7 (0.98) | HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL5403091 | 0.82 | HTR7 (0.96) | HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL5403115 | 0.82 | HTR7 (0.96) | HTR7HTR1A | |
| SCHEMBL8979733 | 0.82 | HTR7 (1.00) | HTR7HTR1A | |
| SCHEMBL7382641 | 0.81 | HTR7 (0.45) | HTR7HTR1ADRD3 | |
| SCHEMBL10035549 | 0.81 | HTR7 (0.94) | HTR7HTR1A | |
| SCHEMBL8979712 | 0.80 | HTR7 (0.80) | HTR7HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL2138966 | 0.80 | HTR7 (0.92) | HTR7HTR1A | |
| SCHEMBL7389513 | 0.79 | HTR7 (0.48) | HTR7HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211585-B2 | 5-HT7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |
| US-7211585-B2 | 5-HT7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |