SCHEMBL14503293

SCHEMBL14503293

CC(C)NC(=O)NC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 11/20 0.67
EPHX1 P07099 4/20 0.67
L3MBTL1 Q9Y468 2/20 0.61
LMNA P02545 2/20 0.60
HTT P42858 1/20 0.60
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 1/20 0.50
JAK2 O60674 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069160 0.81 EPHX2 (1.00) EPHX2EPHX1L3MBTL1LMNAHTT
SCHEMBL74929 0.79 EPHX2 (0.53) EPHX2EPHX1L3MBTL1LMNAHTT
SCHEMBL13923630 0.78 EPHX2 (0.75) EPHX2EPHX1LMNAHTTKMT2A
SCHEMBL16705112 0.78 EPHX2 (0.56) EPHX2EPHX1LMNAHTTKMT2A
SCHEMBL133014 0.77 EPHX1 (0.68) EPHX2EPHX1LMNAHTTKMT2A
SCHEMBL19757636 0.77 EPHX1 (0.68) EPHX2EPHX1LMNAHTTKMT2A
SCHEMBL5559921 0.77 EPHX2 (0.57) EPHX2L3MBTL1LMNAHTTKMT2A
SCHEMBL1065857 0.76 EPHX2 (1.00) EPHX2
SCHEMBL636111 0.76 EPHX2 (0.55) EPHX2EPHX1L3MBTL1LMNAHTT
SCHEMBL636110 0.76 EPHX2 (0.55) EPHX2EPHX1L3MBTL1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed