SCHEMBL133014

SCHEMBL133014

CC(=O)NC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.68
EPHX2 P34913 8/20 0.67
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
SIGMAR1 Q99720 1/20 0.53
GAA P10253 1/20 0.53
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19757636 1.00 EPHX1 (0.68) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
Methyl Alcohol SCHEMBL23645020 0.98 EPHX1 (0.66) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL16037882 0.90
Perchlorate SCHEMBL10990424 0.90 EPHX1 (0.58) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL6058547 0.86 EPHX1 (0.53) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL13977177 0.84 EPHX1 (0.51) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL17226608 0.84 EPHX1 (0.51) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL1032460 0.84 EPHX1 (0.51) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL1032166 0.84 EPHX1 (0.51) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1
SCHEMBL30549313 0.84 EPHX1 (0.51) EPHX1EPHX2KMT2ASMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12469693-B2 Method of forming a carbon-containing layer and structure including the layer ASM IP HOLDING B.V. (NL) 2025-11-11 US claimed
CN-112250594-B Method for preparing 3-acetamido-1-adamantanol 浙江荣耀生物科技股份有限公司 2023-09-12 CN claimed
CN-116217817-A Seed emulsion for covering polymer and preparation method thereof 万华化学集团股份有限公司 2023-06-06 CN claimed
CN-112939798-B Preparation method of amantadine 肯特催化材料股份有限公司 2022-07-19 CN claimed
CN-112939798-A Preparation method of amantadine 浙江理工大学 2021-06-11 CN claimed
CN-112853382-A Electrochemical synthesis method of 1-acetamido adamantane 北京工业大学 2021-05-28 CN claimed
US-20210082692-A1 METHOD OF FORMING A CARBON-CONTAINING LAYER AND STRUCTURE INCLUDING THE LAYER ASM IP HOLDING B.V. (NL) 2021-03-18 US claimed
CN-112250594-A Method for preparing 3-acetamido-1-adamantanol 浙江荣耀生物科技股份有限公司 2021-01-22 CN claimed
US-10613435-B2 Coating solution for resist pattern coating and method for forming pattern NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-04-07 US claimed
CN-109265357-A A kind of synthetic method of amantadine hydrochloride 赵旭萌 2019-01-25 CN claimed
US-20140295350-A1 RESIST PATTERN-FORMING METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2014-10-02 US claimed
US-8481016-B2 Method for inhibition of potential-dependent cation channel KAO CORPORATION (JP) 2013-07-09 US claimed
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel KAO CORPORATION (JP) 2013-02-21 US claimed
US-20120316143-A1 Ophthalmic composition SOLL DAVID B (US) 2012-12-13 US claimed
EP-1989177-B1 AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME UNIV GIESSEN JUSTUS LIEBIG (DE) 2012-08-01 EP claimed
EP-1721888-B1 Process for synthesising aminoadamantanes A M S A ANONIMA MATERIE SINT E (IT) 2010-05-05 EP claimed
US-20090299096-A1 Amidoadamantanes and Method for Producing the Same JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2009-12-03 US claimed
EP-1989177-A1 AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME Justus-Liebig-Universität Giessen (DE) 2008-11-12 EP claimed
WO-2007101535-A1 AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2007-09-13 WO claimed
US-4894180-A Liquid crystal optical element FUJI PHOTO FILM CO., LTD. (JP) 1990-01-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel TRPM7, TRPM8, OR10J3 EPHX1 974/4885EPHX2 1636/4885KMT2A 3964/4885
US-20090299096-A1 Amidoadamantanes and Method for Producing the Same ADORA3, TAAR5, ADORA1 EPHX1 3061/4885EPHX2 1578/4885KMT2A 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.