SCHEMBL14503294

SCHEMBL14503294

O=C(NC1C2CC3CC(C2)CC1C3)C(F)(F)F

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
HSD17B10 Q99714 1/20 0.52
EPHX2 P34913 6/20 0.52
HSD11B1 P28845 3/20 0.48
NPC1 O15118 1/20 0.46
EPHX1 P07099 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10272629 0.80 EPHX2 (0.45) L3MBTL1HSD17B10EPHX2HSD11B1
SCHEMBL13701832 0.79 EPHX2 (0.61) L3MBTL1HSD17B10EPHX2HSD11B1EPHX1
SCHEMBL6346130 0.76 EPHX2 (0.58) L3MBTL1HSD17B10EPHX2HSD11B1EPHX1
SCHEMBL14260927 0.76 EPHX2 (0.58) L3MBTL1HSD17B10EPHX2HSD11B1EPHX1
SCHEMBL3114854 0.76 L3MBTL1 (0.57) L3MBTL1HSD17B10EPHX2HSD11B1NPC1
SCHEMBL3069167 0.75 EPHX2 (0.70) L3MBTL1HSD17B10EPHX2HSD11B1NPC1
SCHEMBL10224990 0.75 EPHX2 (0.41) L3MBTL1HSD17B10EPHX2HSD11B1NPC1
SCHEMBL10284318 0.75 EPHX2 (0.41) L3MBTL1HSD17B10EPHX2HSD11B1NPC1
SCHEMBL16202418 0.73 EPHX2 (0.54) L3MBTL1HSD17B10EPHX2HSD11B1EPHX1
SCHEMBL3805575 0.73 L3MBTL1 (0.59) L3MBTL1HSD17B10EPHX2HSD11B1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed