Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CCR3 | P51677 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428564 | 0.82 | TSHR (0.67) | TSHRMAPTLMNASMN1; SMN2CCR3 | |
| SCHEMBL8119586 | 0.81 | TSHR (0.64) | TSHRMAPTLMNASMN1; SMN2CCR3 | |
| SCHEMBL1124068 | 0.76 | TSHR (0.82) | TSHRMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1124034 | 0.76 | TSHR (0.82) | TSHRMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7241082 | 0.76 | SLC6A2 (0.71) | TSHRMAPTLMNASMN1; SMN2CCR3 | |
| SCHEMBL11321905 | 0.76 | TSHR (0.58) | TSHRMAPTLMNASMN1; SMN2CCR3 | |
| SCHEMBL1124028 | 0.74 | TSHR (0.79) | TSHRMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1124120 | 0.74 | TSHR (0.79) | TSHRMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5596598 | 0.74 | TSHR (0.56) | TSHRMAPTLMNASMN1; SMN2CCR3 | |
| SCHEMBL6290794 | 0.73 | GBA1 (0.63) | CCR3POLBSLC18A3PRMT3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |