Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119586 | 0.85 | TSHR (0.64) | TSHRCCR3MAPTSMN1; SMN2HTT | |
| SCHEMBL5596677 | 0.80 | CARM1 (0.45) | LMNACARM1PRMT6PRMT8KDM4E | |
| SCHEMBL11321905 | 0.77 | TSHR (0.58) | TSHRCCR3MAPTSMN1; SMN2HTT | |
| SCHEMBL5801122 | 0.76 | MAPT (0.66) | TSHRMAPTSMN1; SMN2HTTNPC1 | |
| SCHEMBL14503465 | 0.74 | TSHR (0.74) | TSHRCCR3MAPTSMN1; SMN2HTT | |
| SCHEMBL10107366 | 0.74 | AVPR1A (0.55) | TSHRCCR3MAPTSMN1; SMN2HTT | |
| SCHEMBL5596259 | 0.73 | LMNA (0.50) | TSHRMAPTSMN1; SMN2HTTNPC1 | |
| SCHEMBL5597095 | 0.72 | KDM4E (0.41) | MAPTHTTLMNAALDH1A1KDM4E | |
| SCHEMBL7241082 | 0.72 | SLC6A2 (0.71) | TSHRCCR3MAPTSMN1; SMN2HTT | |
| SCHEMBL3513447 | 0.71 | KDM4E (0.36) | TSHRMAPTSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |