Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010368 | 0.88 | TK1 (0.46) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL23083205 | 0.88 | TK1 (0.46) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL15893331 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL16180381 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL657377 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL24254562 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL15893328 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL16180380 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL15895622 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 | |
| SCHEMBL11780860 | 0.75 | TK1 (0.43) | TK1TK2LMNASMN1; SMN2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220730-B2 | Cancer specific radiolabeled conjugates regulated by the cell cycle for the treatment and diagnosis of cancer | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2007-05-22 | — | — | US | disclosed |