Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYBB | P04839 | 1/20 | 0.37 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.37 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391464 | 1.00 | MAPT (0.40) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5380923 | 0.99 | MAPT (0.41) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL14428629 | 0.96 | MAPT (0.39) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5384918 | 0.95 | MAPT (0.38) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5391100 | 0.95 | CAMK1D (0.39) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL14428604 | 0.95 | CAMK1D (0.39) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5400876 | 0.95 | CAMK1D (0.39) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5387463 | 0.92 | MAPT (0.36) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5378133 | 0.92 | CTNNB1 (0.40) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5380874 | 0.92 | ALDH1A1 (0.46) | MAPTPTGS2SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |