Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2138969 | 0.99 | HTR7 (0.61) | HTR7HTR6MAPT | |
| SCHEMBL8980463 | 0.97 | HTR7 (0.63) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4228093 | 0.96 | HTR7 (0.62) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| SCHEMBL8981052 | 0.96 | HTR7 (0.62) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4228924 | 0.95 | HTR7 (0.61) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| SCHEMBL8980721 | 0.93 | HTR7 (0.63) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4228305 | 0.92 | HTR7 (0.62) | HTR7HTR6HDAC3HDAC1HDAC2 | |
| SCHEMBL10035532 | 0.91 | HTR7 (0.59) | HTR7HTR6MAPTTP53 | |
| SCHEMBL8981627 | 0.88 | HTR7 (0.68) | HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL4218317 | 0.87 | HTR7 (0.67) | HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211584-B2 | 5-HT7 receptor ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |
| US-7211584-B2 | 5-HT7 receptor ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |